Analysis of the distribution of infectious bacteria and the status of drug resistance in hospitalized patients of hematology department
10.3760/cma.j.cn115356-20200924-00236
- VernacularTitle:血液科住院患者感染细菌分布及耐药情况分析
- Author:
Ziyuan SHEN
1
;
Haiquan KANG
;
Yingliang JIN
;
Wei SANG
Author Information
1. 徐州医科大学公共卫生学院流行病与卫生统计学系，徐州 221004
- Keywords:
Hematologic diseases;
Inpatients;
Infection;
Drug resistance;
Drug resistance
- From:
Journal of Leukemia & Lymphoma
2022;31(1):42-45
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the bacterial distribution of secondary infection and the status of drug resistance in hospitalized patients of hematology department.Methods:The clinical data of 1 125 inpatients in the Hematology Department of the Affiliated Hospital of Xuzhou Medical University from January 2015 to December 2019 were retrospectively analyzed, and the distribution of infectious pathogens and the status of drug resistance of these inpatients were analyzed.Results:A total of 9 335 microbial samples from 1 125 inpatients were submitted for examination, among which 1 349 were positive samples. Among 1 349 positive samples, the gram-negative bacteria-positive samples accounted for 66.4% (895/1 349) and the gram-positive bacteria-positive samples accounted for 33.7% (454/1 349); the blood samples accounted for 44.7%(603/1 349), the sputum samples accounted for 33.9% (457/1 349), and the urine samples accounted for 9.4%(127/1 349). The isolated bacteria whose proportion ranked as the top 3 were Escherichia coli (31.0%), Staphylococcus aureus (21.0%) and Klebsiella pneumoniae (18.0%). The drug resistance rate of Escherichia coli to ceftriaxone was as high as 77.2%, and that of Staphylococcus aureus and coagulase-negative Staphylococcus to benzoxicillin was 58.2% and 66.7%, but both had no resistance to vancomycin.Conclusions:There are a wide variety of infectious pathogens in hospitalized patients of hematology department, and the Escherichia coli and Klebsiella pneumonia are predominant. More attention should be paid to antibiotic prescribing training for clinicians to optimize and standardize the use of antibiotics.
