Effect of early individualized rehabilitation on patients with severe mechanical ventilation
10.3969/j.issn.1006-9771.2022.06.013
- VernacularTitle:重症机械通气患者早期个体化康复的效果
- Author:
Jing MAO
1
;
Xiaoxiao TANG
1
;
Yao ZHENG
2
;
Jinniu ZHANG
1
;
Xiuli KAN
1
;
Jianxian WU
1
Author Information
1. Department of Rehabilitation Medicine, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230601, China
2. Intensive Care Unit, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230601, China
- Publication Type:Journal Article
- Keywords:
mechanical ventilation;
early individualized rehabilitation;
intensive care unit
- From:
Chinese Journal of Rehabilitation Theory and Practice
2022;28(6):710-715
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the effect of early individualized rehabilitation on patients with severe mechanical ventilation. MethodsA total of 36 patients on mechanical ventilation admitted to the ICU of the Second Affiliated Hospital of Anhui Medical University from March, 2019 to February, 2020 were randomly divided into control group (n = 18) and rehabilitation group (n = 18). All the patients completed a rehabilitation assessment within 24 hours of admission, including clinical assessment, state of consciousness and muscle strength assessment. The control group was treated with intensive care routine treatment, including symptomatic treatment of primary disease, nutritional support, placement of normal limbs, active and passive movement of limbs. The rehabilitation group received early individualized rehabilitation in addition., including active and passive limb movements, transfer training, physical factor therapy, and respiratory muscle training after the specific evaluation. The mechanical ventilation duration and ICU length of stay, the hospitalization cost, Richmond Agitation and Sedation Scale (RASS), acute Physiology and Chronic Health Evaluation Ⅱ (APACHEⅡ), and the content of tumor necrosis factor (TNF)-α, interleukin (IL)-6 and IL-8 were compared. ResultsThere was no significant difference in the weaning rate and hospitalization cost between two groups (P > 0.05). The mechanical ventilation duration and ICU length of stay were less in the rehabilitation group than in the control group (t > 2.067, P < 0.05). After treatment, the score of APACHEⅡ and the content of TNF-α and IL-6 decreased in the control group (t > 2.040, P < 0.05); the score of APACHEⅡ and the content of TNF-α, IL-6 and IL-8 decreased in the rehabilitation group (t > 4.141, P < 0.001); the content of TNF-α, IL-6 and IL-8 was less in the rehabilitation group than in the control group (t > 2.217, P < 0.05). The improvement of all the indexes was better in the rehabilitation group than in the control group (|Z| > 2.104, P < 0.05). ConclusionFor patients on mechanical ventilation, early individualized rehabilitation could improve the sedation, relieve the inflammatory reaction, accelerate the process of weaning, and reduce the length of stay with no extra cost.
