Primary amelanotic melanoma of the cervix: case report with review of literature.
10.3802/jgo.2010.21.3.199
- Author:
Rajan DUGGAL
1
;
Radhika SRINIVASAN
Author Information
1. Department of Cytopathology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. drsradhika@gmail.com
- Publication Type:Case Report
- Keywords:
Aamelanotic melanoma;
HMB-45 antibody
- MeSH:
Aged;
Cervix Uteri;
Female;
Hemorrhage;
Humans;
Immunohistochemistry;
Melanoma;
Melanoma, Amelanotic;
Prognosis;
S100 Proteins;
Surgical Instruments;
Uterine Cervical Neoplasms
- From:Journal of Gynecologic Oncology
2010;21(3):199-202
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary malignant melanoma of the uterine cervix is a rare neoplasm with poor prognosis. It may be misdiagnosed especially when amelanotic, in which case immunohistochemistry is useful in reaching the diagnosis. We present one such case of a 65-year-old postmenopausal female patient presenting with bleeding per vaginum. Speculum examination revealed an ulcero-proliferative growth involving the cervix. On histopathological examination it was originally suspected to be a poorly differentiated carcinoma or a non-epithelial malignant tumor, but was subsequently correctly diagnosed by immunohistochemical staining with the HMB-45 antibody and S-100 protein.
