Osteoporosis and risk factors in perimenopausal women
10.19428/j.cnki.sjpm.2022.21488
- VernacularTitle:围绝经期女性骨质疏松症及相关因素分析
- Author:
Beibei LI
1
;
Hong LIU
1
;
Yong WANG
1
;
Yibiao DING
1
;
Qian SHE
1
Author Information
1. Gaoqiao Community Health Service Center， Pudong New Area， Shanghai 200137， China
- Publication Type:Journal Article
- Keywords:
perimenopausal women;
menopause;
bone mineral density;
osteoporosis;
related factor
- From:
Shanghai Journal of Preventive Medicine
2022;34(5):469-474
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo screen the risk factors of osteoporosis in perimenopausal women， and to provide direction for timely prevention and treatment. MethodsUsing multilevel stratified random sampling method， the perimenopausal women were investigated by questionnaire survey， and the determination of bone mineral density （BMD） and the levels of several important hormones. ResultsA total of 720 valid questionnaires were received. Among 720 perimenopausal women， 173 had osteoporosis and 547 had no osteoporosis. Univariate analysis of the influencing factors of osteoporosis showed that the levels of parathyroid hormone （PTH）， Estradiol （E2）， body mass index （BMI）， age， time of last period and age of menopause were significantly different among perimenopausal women in the prevalence of osteoporosis（χ2=4.23， 4.86， 16.06， 21.04， 10.52， 13.02； P<0.05）.Logistic regression analysis showed that the increase of PTH （OR=2.70， P<0.05）and menopause （OR=1.76， P<0.05） were the risk factors of osteoporosis . Higher BMI（OR=0.65， P<0.05）， higher personal monthly income（OR=0.72， P<0.05）， longer sunshine time（OR=0.69， P<0.05）， were the protective factors against osteoporosis. ConclusionThe increase of PTH levels and menopause are the risk factors for osteoporosis in women. Perimenopausal women should be monitored for bone mineral density and appropriate intervention. Necessary treatment measures should be taken for the patients with osteopenia and osteoporosis.
