The spatial-temporal characteristics of hand-foot-mouth disease in Minhang District of Shanghai， 2009‒2020
10.19428/j.cnki.sjpm.2022.21373
- VernacularTitle:上海市闵行区2009—2020年手足口病疫情时空流行特征
- Author:
Yating WANG
1
;
Wei ZHONG
2
;
Jinhua PAN
1
;
Zhaowen ZHANG
2
;
Jingjing ZHANG
2
;
Jing LYU
2
;
Biyun JIA
2
;
Zhouyun WANG
2
;
Wanli CHEN
2
;
Xuanzhao ZHANG
2
;
Hualin SU
2
;
Minhui ZHU
2
;
Zhiyin XU
2
Author Information
1. Department of Epidemiology， School of Public Health， Key Laboratory of Public Health Safety of Ministry of Education， Fudan University， Shanghai 200032， China
2. Minhang District Center for Disease Control and Prevention， Shanghai 201101， China
- Publication Type:Journal Article
- Keywords:
hand-foot-mouth disease;
epidemiological characteristics;
geographical information system;
etiology
- From:
Shanghai Journal of Preventive Medicine
2022;34(5):441-445
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveThis study aimed to understand the epidemiological characteristics of hand-foot-mouth disease （HFMD） in Minhang District， Shanghai from 2009 to 2020， and provide a scientific basis for the prevention and control of HFMD. MethodsThe case information of HFMD was collected from the National Notifiable Infectious Diseases Reporting System of Chinese Center for Disease Control and Prevention. We used descriptive epidemiological methods to analyze the population characteristics， temporal and spatial distribution of HFMD， the pathogen composition of the case and its changing trend. ResultsFrom 2009 to 2020， a total of 66，198 cases of HFMD were reported in Minhang District， Shanghai， including 377 severe cases （severe case rate 0.57%） and 3 deaths （severs case fatality rate 0.80%）. There were more cases of HFMD in boys than in girls （1.5∶1）. HFMD patients aged under 5 years predominated， accounting for 88.91% of all cases. Majority of the cases （91.42%） were in scattered children （55.80%） and children in kindergartens （35.62%）. The incidence showed a cyclical trend， with low incidence years and high incidence years appearing alternately. The peak period was from April to July， and sometimes there were small peaks during October to December. A total of 12 years time-space scanning analysis revealed 3 clusters. The cluster centers were located in Wujing Town， Huacao Town and Xinzhuang Town， respectively. The proportion of EV71 in common cases was generally decreasing， and reduced to zero in 2019. The proportion of CoxA6 had increased year by year， and reached 75.00% in 2020. CoxA6 became the dominant pathogen in recent years. The number of severe cases had decreased year by year since 2010， and the dominant pathogen was EV71 （90.03% on average） in severe cases. ConclusionThe incidence of HFMD in Minhang District of Shanghai has a downward trend from 2014. The dominant pathogen changes from EV71 to CoxA6， and the dominant pathogen in severe cases is EV71. The discovered temporal and spatial clustering pattern is helpful for in-depth understanding of the distribution and epidemic trend of HFMD in Minhang District， and provides a scientific basis for epidemic prevention and control.
