A pair of new phenylpropanoid enantiomers from Cordia dichotoma fruits
10.16438/j.0513-4870.2021-1727
- VernacularTitle:破布木果中一对新的苯丙素对映异构体
- Author:
Feng WEI
1
;
Jing-tong DENG
2
;
Hai-tao CHENG
2
;
Ke-jian PANG
1
;
Xin-zhou YANG
2
Author Information
1. Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, School of Pharmacy, Shihezi University, Shihezi 832003, China
2. School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China
- Publication Type:Research Article
- Keywords:
italic>Cordia dichotoma;
chemical composition;
phenylpropanoid;
enantiomers;
cordilide
- From:
Acta Pharmaceutica Sinica
2022;57(6):1863-1867
- CountryChina
- Language:Chinese
-
Abstract:
The ethyl acetate part of the alcoholic extract of Cordia dichotoma fruits was purified by a combination of normal-phase silica gel column chromatography, Sephadex LH-20 gel column chromatography and semi-preparative HPLC, and the structure was identified by modern spectroscopic techniques (UV, IR, MS, NMR). A total of 10 compounds were isolated and identified as cordilide (1), (S)-2-hydroxy-3-(4′-hydroxyphenyl) propanoic acid (2), vanillic acid (3), p-coumaric acid (4), 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one (5), benzoic acid (6), p-hydroxypropiophenone (7), p-hydroxyacetophenone (8), 5′-methoxyevofolin B (9) and vanillin (10). Among them, compound 1 is a pair of new phenylpropanoid enantiomers, and compounds 3, 6, 8 and 9 were isolated for the first time from the genus.
