Genomic instability as a major mechanism for acquired resistance to EGFR tyrosine kinase inhibitors in cancer.
10.1007/s13238-021-00855-6
- Author:
Bing LIU
1
;
Daniela DUENAS
1
;
Li ZHENG
1
;
Karen RECKAMP
2
;
Binghui SHEN
3
Author Information
1. Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, 1500 East Duarte Road, Duarte, CA, 91010, USA.
2. Division of Medical Oncology, Cedars-Sinai Medical Center, 8700 Beverly Blvd, West Hollywood, CA, 90048, USA.
3. Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, 1500 East Duarte Road, Duarte, CA, 91010, USA. bshen@coh.org.
- Publication Type:Review
- MeSH:
Carcinoma, Non-Small-Cell Lung/genetics*;
Drug Resistance, Neoplasm/genetics*;
ErbB Receptors/metabolism*;
Genomic Instability;
Humans;
Lung Neoplasms/genetics*;
Neoplasm Proteins/metabolism*;
Protein Kinase Inhibitors/therapeutic use*
- From:
Protein & Cell
2022;13(2):82-89
- CountryChina
- Language:English
