Maternal heterozygous mutation in CHEK1 leads to mitotic arrest in human zygotes.
10.1007/s13238-021-00844-9
- Author:
Beili CHEN
1
;
Jianying GUO
2
;
Ting WANG
2
;
Qianhui LEE
3
;
Jia MING
2
;
Fangfang DING
1
;
Haitao LI
2
;
Zhiguo ZHANG
4
;
Lin LI
5
;
Yunxia CAO
6
;
Jie NA
7
Author Information
1. Department of Obstetrics and Gynecology, Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
2. School of Medicine, Tsinghua University, Beijing, 100084, China.
3. Department of Chemistry, Tsinghua University, Beijing, 100084, China.
4. Department of Obstetrics and Gynecology, Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. zzg_100@163.com.
5. Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China. linlithu@ccmu.edu.cn.
6. Department of Obstetrics and Gynecology, Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. caoyunxia6@126.com.
7. School of Medicine, Tsinghua University, Beijing, 100084, China. jie.na@tsinghua.edu.cn.
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Cell Cycle Checkpoints/genetics*;
Checkpoint Kinase 1/metabolism*;
Heterozygote;
Humans;
Mitosis/genetics*;
Mutation;
Zygote/metabolism*
- From:
Protein & Cell
2022;13(2):148-154
- CountryChina
- Language:English
