Biomechanical Study of New Biodegradable Esophageal Stent.
10.3969/j.issn.1671-7104.2022.02.002
- Author:
Wentao YAN
1
;
Hongyi YU
1
;
Biao DING
1
;
Zhongwei ZHENG
2
;
Hang YAN
2
;
Shengli LIN
3
;
Pinghong ZHOU
3
Author Information
1. Shanghai Institute of Medical Device Testing, Shanghai, 201318.
2. Shanghai Elitek Biosciences Co. Ltd., Shanghai, 200131.
3. Center of Endoscopy, Zhongshan Hospital, Fudan University, Shanghai, 200032.
- Publication Type:Journal Article
- Keywords:
biodegradation;
esophageal stent;
finite element analysis;
radial force
- MeSH:
Esophageal Stenosis/surgery*;
Finite Element Analysis;
Humans;
Mechanical Phenomena;
Stents
- From:
Chinese Journal of Medical Instrumentation
2022;46(2):126-131
- CountryChina
- Language:Chinese
-
Abstract:
The radial force of the degradable esophageal stent before and after degradation is one of the important indicators for effective treatment of esophageal stricture. Based on a combination of in vitro experiments and finite element analysis, this paper studies and verifies the biomechanical properties of a new type of degradable esophageal stent under different esophageal stricture conditions. Under radial extrusion conditions, the maximum stress at the port of the stent is 65.25 MPa, and the maximum strain is 1.98%; The peak values of stress and strain under local extrusion and plane extrusion conditions both appear in the extrusion area and the compression expansion area at both ends, which are respectively 48.68 MPa, 46.40 MPa, 0.49%, 1.13%. The maximum radial force of the undegraded stent was 11.22 N, and 97% and 51% of the maximum radial force were maintained after 3 months and 6 months of degradation, respectively. The research results verify the safety and effectiveness of the radial force of the new degradable esophageal stent, and provide a theoretical basis for the clinical treatment of esophageal stricture.
