Trauma-induced pulmonary thromboembolism: What's update?
10.1016/j.cjtee.2021.08.003
- Author:
Yu-Hong MI
1
;
Ming-Ying XU
2
Author Information
1. Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vascular Disease, Beijing, 100029, China. Electronic address: myhicu@163.com.
2. Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vascular Disease, Beijing, 100029, China.
- Publication Type:Review
- Keywords:
Deep venous thrombosis;
Etiology;
Prevention;
Pulmonary thromboembolism;
Treatment;
Venous thromboembolism;
Wounds and injuries
- MeSH:
Anticoagulants/adverse effects*;
Hemorrhage;
Humans;
Pulmonary Embolism/prevention & control*;
Risk Factors;
Venous Thromboembolism/prevention & control*
- From:
Chinese Journal of Traumatology
2022;25(2):67-76
- CountryChina
- Language:English
-
Abstract:
Trauma-induced pulmonary thromboembolism is the second leading cause of death in severe trauma patients. Primary fibrinolytic hyperactivity combined with hemorrhage and consequential hypercoagulability in severe trauma patients create a huge challenge for clinicians. It is crucial to ensure a safe anticoagulant therapy for trauma patients, but a series of clinical issues need to be answered first, for example, what are the risk factors for traumatic venous thromboembolism? How to assess and determine the status of coagulation dysfunction of patients? When is the optimal timing to initiate pharmacologic prophylaxis for venous thromboembolism? What types of prophylactic agents should be used? How to manage the anticoagulation-related hemorrhage and to determine the optimal timing of restarting chemoprophylaxis? The present review attempts to answer the above questions.
