Mixed bacterial-fungal infection following total hip arthroplasty: A case report.
10.1016/j.cjtee.2021.07.010
- Author:
Yang-Jing LIN
1
;
Tiao SU
1
;
Liu YANG
1
;
Guang-Xing CHEN
2
Author Information
1. Department of Joint Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, China.
2. Department of Joint Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, China. Electronic address: cgx7676@hotmail.com.
- Publication Type:Case Reports
- Keywords:
Arthroplasty;
Candida albicans;
Hip;
Prosthesis-related infections;
Staphylococcus hominis
- MeSH:
Aged;
Anti-Bacterial Agents/therapeutic use*;
Arthroplasty, Replacement, Hip/adverse effects*;
Debridement;
Female;
Fungi;
Hip Prosthesis/adverse effects*;
Humans;
Mycoses/drug therapy*;
Prosthesis-Related Infections/therapy*;
Reoperation;
Retrospective Studies;
Treatment Outcome
- From:
Chinese Journal of Traumatology
2022;25(1):32-36
- CountryChina
- Language:English
-
Abstract:
Prosthetic infection is one of the severe postoperative complications of arthroplasty. Mixed bacterial-fungal prosthetic infection is rare but can be disastrous. This case was a 76-year-old female suffered from prosthetic infection following total hip replacement due to femoral neck fracture and underwent multiple debridements. The culture of periprosthetic tissue was bacteriologically sterile following the first debridement, while the Staphylococcus hominis was identified in the second debridement in the previous hospitalization where fungal infection had not been considered. Thus the pathogen spectrum of anti-infection therapy failed to contain fungus. Ultimately, the culture result of our sampled periprosthetic tissue during the third debridement was Candida albicans without bacterium in our hospital. The fungal prosthetic infection was successfully treated by a two-stage revision with antifungal drugs. Accurate diagnosis and standardized treatment is the key to the therapy of infection after hip arthroplasty, especially for mixed bacterial-fungal prosthetic infection.
