Pseudomembranous Colitis Caused by Clostridium Difficile.
- Author:
Sung Min CHO
;
Chang Don LEE
;
Wan Kook LEE
;
In Sik CHUNG
;
Kyung Hee KIM
;
Kyu Won CHUNG
;
Hee Sik SUN
;
Whan Kook CHUNG
- Publication Type:Original Article
- MeSH:
Abdominal Pain;
Anti-Bacterial Agents;
Biopsy;
Clindamycin;
Clostridium difficile*;
Clostridium*;
Diarrhea;
Enteritis;
Enterocolitis, Pseudomembranous*;
Humans;
Male;
Strikes, Employee;
Vancomycin
- From:Korean Journal of Gastrointestinal Endoscopy
1985;5(1):67-71
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pseudomembranous colitis (PMC) was first described by Finney as postoperative diphtheritic enteritis in 1893 and was known to be associated with antibiotics by Reiner et al in 1952. Most cases of antibiotic-associated PMC are now associated with cytotoxigenic C. difficile. The association of PMC several antibiotics is well docamented; however, its association with clindamycin appeared to be most striking. We experienced a male patient who developed tarry stool, abdominal pain and diarrhea after having recieved clindamycin for two weeks. The PMC diagnosed by colonofiberscopy with biopsy and C. difficile was identified by tissue-culture study. The patient was treated by oral vancomycin and healed. Described here a case of PMC with some review of literature.
