Steroids from Uncaria rhynchophylla.
10.19540/j.cnki.cjcmm.20211012.204
- Author:
Xin-Yu LIU
1
;
Xing-Zi HOU
1
;
Qiang GUO
1
;
Peng-Fei TU
1
;
Qing-Ying ZHANG
1
Author Information
1. State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center Beijing 100191, China.
- Publication Type:Journal Article
- Keywords:
Uncaria rhynchophylla;
chemical constituent;
steroid
- MeSH:
Chromatography, High Pressure Liquid;
Steroids;
Uncaria/chemistry*
- From:
China Journal of Chinese Materia Medica
2022;47(3):684-691
- CountryChina
- Language:Chinese
-
Abstract:
Thirteen steroids(1-13) were isolated from the non-alkaloid constituents of Uncaria rhynchophylla by column chromatography on silica gel, ODS, Sephadex LH-20, and preparative HPLC chromatography, and their structures were elucidated by analyses of the MS and NMR spectral data. All the compounds were isolated from the genus Uncaria for the first time, and 1 was a new compound. The ~1H-NMR and ~(13)C-NMR data of two compounds(12 and 13) in deuteron-chloroform were completely assigned. This study enriched the steroid constituents of U. rhynchophylla and provided scientific references for the elucidation of active constituents and further development and utilization of U. rhynchophylla.
