Residual status, toxicity, and analytical method of banned pesticides in traditional Chinese medicines.
10.19540/j.cnki.cjcmm.20211014.202
- Author:
Xin-Qi SUN
1
;
Fang AN
2
;
Qian LU
3
;
Chun-Yu LI
4
;
Jiao-Yang LUO
3
;
Mei-Hua YANG
3
Author Information
1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100193, China School of Pharmacy, Hebei North University Zhangjiakou 075000, China.
2. School of Pharmacy, Hebei North University Zhangjiakou 075000, China.
3. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100193, China.
4. National Clinical Research Center for Cancer, National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100021, China.
- Publication Type:Review
- Keywords:
analytical method;
banned pesticides;
residual status;
toxicity;
traditional Chinese medicines
- MeSH:
China;
Drugs, Chinese Herbal/toxicity*;
Humans;
Medicine, Chinese Traditional;
Organophosphorus Compounds;
Pesticide Residues/toxicity*;
Pesticides/analysis*
- From:
China Journal of Chinese Materia Medica
2022;47(3):611-627
- CountryChina
- Language:Chinese
-
Abstract:
A total of 33 pesticides have been banned from Chinese medicinal materials and decoction pieces(plants) according to Chinese Pharmacopoeia(2020 edition). According to the chemical structures, they are mainly divided into seven categories: organophosphorus compounds, organochlorines, carbamates, amidines, sulfonylureas, phenylpyrazoles, and ethers. These banned pesticides exhibit neurotoxicity, reproductive toxicity, immune system toxicity, teratogenicity, carcinogenesis, and mutagenesis, seriously damaging human and animal health. They affect not only the quality and safety of traditional Chinese medicines and resulting products, but also their competitiveness in the international market. Due to the numerous varieties of traditional Chinese medicines and their complex substrates, it is necessary to establish a universal and highly sensitive method for pesticide residue detection. This review systematically summarized the residual status, toxicity, and analytical methods of banned pesticides in traditional Chinese medicines, and forecasted the prospects of different analytical techniques, so as to provide reference for further safety and risk assessment of banned pesticide residues in traditional Chinese medicines, thus ensuring the safe production of traditional Chinese medicines.
