Construction of quality evaluation strategy for Chinese medicine based on ambient mass spectrometry.
10.19540/j.cnki.cjcmm.20210712.602
- Author:
Chang-Jiang-Sheng LAI
1
;
Zi-Dong QIU
1
;
Xu-Ya WEI
1
;
Ze-Yan CHEN
1
Author Information
1. State Key Laboratory Breading Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
- Publication Type:Journal Article
- Keywords:
ambient mass spectrometry;
data processing;
quality evaluation of Chinese medicine;
quality tracing;
real-time monitoring;
toxicity grading
- MeSH:
China;
Drugs, Chinese Herbal;
Mass Spectrometry;
Medicine, Chinese Traditional;
Nonprescription Drugs;
Reference Standards
- From:
China Journal of Chinese Materia Medica
2022;47(1):279-284
- CountryChina
- Language:Chinese
-
Abstract:
Quality is the guarantee for the clinical safety and effectiveness of Chinese medicine. Accurate quality evaluation is the key to the standardization and modernization of Chinese medicine. Efforts have been made in improving Chinese medicine quality and strengthening the quality and safety supervision in China, but rapid and accurate quality evaluation of complex Chinese medicine samples is still a challenge. On the basis of the development of ambient mass spectrometry and the application in quality evaluation of complex Chinese medicine systems in recent years, the authors developed the multi-scenario Chinese medicine quality evaluation strategies. A systematic methodology was proposed in specific areas such as real-time monitoring of the quality of complex Chinese medicine decoction system, rapid toxicity grading of compound Chinese patent medicine, and evaluation of bulk medicinals of Chinese patent medicine. Allowing multi-scenario analysis of Chinese medicine, it is expected to provide universal research ideas and technical methods for rapid and accurate quality evaluation of Chinese medicine and boost the high-quality development of Chinese medicine industry.
