Research status on efficacy enhancement and toxicity reduction of Chinese medicine in treatment of malignant tumors: a review of projects supported by National Natural Science Foundation of China.
10.19540/j.cnki.cjcmm.20211104.301
- Author:
Xue-Wei LIU
1
;
Yan-Ni LOU
2
;
Zhe FENG
3
;
Li-Wei HAN
4
Author Information
1. Department of Health Sciences, National Natural Science Foundation of China Beijing 100085, China Mental Health College, Qiqihar Medical University Qiqihar 161006, China.
2. Department of Oncology of Integrated Chinese and Western Medicine, China-Japan Friendship Hospital Beijing 100029, China.
3. Department of Health Sciences, National Natural Science Foundation of China Beijing 100085, China The First Clinical Medical College, Nanjing University of Chinese Medicine Nanjing 210023, China.
4. Department of Health Sciences, National Natural Science Foundation of China Beijing 100085, China.
- Publication Type:Review
- Keywords:
Chinese medicine;
National Natural Science Foundation of China;
efficacy enhancement;
toxicity reduction;
tumor
- MeSH:
China;
Foundations;
Humans;
Medicine, Chinese Traditional;
Natural Science Disciplines;
Neoplasms/drug therapy*;
Retrospective Studies
- From:
China Journal of Chinese Materia Medica
2022;47(1):253-258
- CountryChina
- Language:Chinese
-
Abstract:
Through a retrospective analysis of the projects supported by the National Natural Science Foundation of China in the past ten years in the field of Chinese medicine for the treatment of malignant tumors, this article systematically summarized the main research contents and hotspots of Chinese medicine in efficacy enhancement and toxicity reduction. The efficacy enhancement of Chinese medicine mainly included the mitigation of molecule-targeted drug resistance, multidrug resistance, and chemotherapy resistance, synergistic efficacy enhancement, and radiotherapy sensitization. The toxicity reduction is mainly reflected in the alleviation of the side effects of radiotherapy and chemotherapy. In addition, Chinese medicine has advantages in reducing serious adverse reactions of malignant tumors, providing more options for the adjuvant treatment of tumors.