Quality standard of Lobeliae Chinensis Herba.
10.19540/j.cnki.cjcmm.20210906.201
- Author:
Qian ZHANG
1
;
Hui-Xia HUO
1
;
Hui-Na YAO
1
;
Yun-Fang ZHAO
1
;
Peng-Fei TU
2
;
Jun LI
1
;
Qing-Ying ZHANG
3
Author Information
1. Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China.
2. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center Beijing 100191, China.
3. Department of Natural Medicines,School of Pharmaceutical Sciences, Peking University Health Science Center Beijing 100191, China.
- Publication Type:Journal Article
- Keywords:
HPLC;
Lobeliae Chinensis Herba;
TLC;
characteristic chromatogram;
quality standard
- MeSH:
Chromatography, High Pressure Liquid;
Drugs, Chinese Herbal/standards*;
Lobelia/chemistry*;
Plants, Medicinal/chemistry*
- From:
China Journal of Chinese Materia Medica
2022;47(1):127-133
- CountryChina
- Language:Chinese
-
Abstract:
In light of related methods in Chinese Pharmacopoeia(2020 edition), this study established the quality standard for Lobeliae Chinensis Herba. The TLC identification method was established with silica gel GF_(254) thin layer plate, diosmin standard, linarin standard, and the reference material of Lobeliae Chinensis Herba. The loss on drying, total ash, acid-insoluble ash, and ethanol-soluble extracts of 18 batches of Lobeliae Chinensis Herba samples were determined according to the general principles in Chinese Pharmacopoeia. Then, HPLC was adopted in the establishment of characteristic chromatogram and content determination. The results showed that the established method can achieve good separation for diosmin, linarin, and lobetyolin. Based on the results of detection for 18 batches of Lobeliae Chinensis Herba samples, the draft quality standard was established, which was expected to provide reference for the revision of this medicinal herb in Chinese Pharmacopoeia.
