Androgen Insensitivity Syndrome with Bilateral Cryptorchidism and Seminoma in Tibet:Report of One Case.
10.3881/j.issn.1000-503X.13544
- Author:
Qian WEI
1
;
Zhen DA
1
;
Qu-Zhen CIREN
1
;
Zhen HUO
2
;
Peng ZUO
3
Author Information
1. Department of Pathology,Tibet Autonomous Region People's Hospital,Lhasa 850000,China.
2. Department of Pathology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
3. Department of Obstetrics and Gynaecology,Peking University People's Hospital,Beijing 100044,China.
- Publication Type:Journal Article
- Keywords:
Tibet;
androgen insensitivity syndrome;
cryptorchidism;
pelvic cavity;
seminoma
- MeSH:
Androgen-Insensitivity Syndrome/surgery*;
Cryptorchidism;
Female;
Humans;
Male;
Seminoma/pathology*;
Testicular Neoplasms/pathology*;
Tibet
- From:
Acta Academiae Medicinae Sinicae
2022;44(1):173-176
- CountryChina
- Language:Chinese
-
Abstract:
Androgen insensitivity syndrome(AIS)with bilateral testicular malignant transformation is very rare,and its diagnosis should be based on clinical manifestations,physical examination,serological findings,karyotype analysis,and pathological findings.This study reported a case of complete androgen insensitivity syndrome among Tibetan in Tibet.It took 17 years from the discovery of congenital absence of uterus to bilateral pelvic mass resection.Pathological examination confirmed that bilateral pelvic space occupying lesions were dysplastic testicular tissue with seminoma and sertoli cell adenoma-like nodules.This study summarized the clinicopathological features to deepen the understanding of the disease.