Research Progress of Fibroblast Growth Factor Receptor Signaling Pathway in Breast Cancer.
10.3881/j.issn.1000-503X.12873
- Author:
Qiu-Sheng GUO
1
;
Wen-Ming CAO
2
;
Xiao-Jia WANG
2
Author Information
1. Zhejiang Chinese Medical University,Hangzhou 310053,China.
2. Department of Medical Oncology (Breast Cancer),Cancer Hospital of the University of Chinese Academy of Sciences,Hangzhou 310022,China.
- Publication Type:Journal Article
- Keywords:
breast cancer;
fibroblast growth factor receptor;
signal transduction;
targeted therapy
- MeSH:
Apoptosis;
Breast Neoplasms/metabolism*;
Female;
Humans;
Receptors, Fibroblast Growth Factor/metabolism*;
Signal Transduction
- From:
Acta Academiae Medicinae Sinicae
2022;44(1):136-141
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer,one of the common malignant tumors in women,has shown rising incidence in recent years,posing a serious threat to women's health.The advancement of molecular biology facilitates the revealing of the relationships between signaling pathways and breast cancer.Fibroblast growth factor receptor (FGFR) signaling pathway plays an important role in the proliferation,survival,differentiation,migration,and apoptosis of breast cancer cells.Strategies targeting the FGFR signaling pathway thus exhibit a promising prospect in breast cancer treatment.
