Cardiac Protection Mechanism and Clinical Application of Dexmedetomidine.
10.3881/j.issn.1000-503X.12895
- Author:
Yi-Cheng YANG
1
;
Bei-Er CHEN
2
;
Kai-Yan YE
3
;
Wan-Ying HE
4
;
Zhi-Qiang XIAO
5
;
Chang-Ming XIONG
1
Author Information
1. Department of Cardiology,Fuwai Hospital,CAMS and PUMC,Beijing 100037,China.
2. Department of Pharmacoeconomics,School of Pharmacy,University of Southern California, Los Angeles,California 90007,USA.
3. The Second Clinical Medical College,Southern Medical University,Guangzhou 510515,China.
4. Department of Anesthesiology,Zhujiang Hospital,Southern Medical University,Guangzhou 510515,China.
5. State Key Laboratory of Ophthalmology,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangzhou 510060,China.
- Publication Type:Review
- Keywords:
cardiac protection;
dexmedetomidine;
perioperative period;
surgery
- MeSH:
Dexmedetomidine/therapeutic use*;
Heart;
Humans
- From:
Acta Academiae Medicinae Sinicae
2022;44(1):130-135
- CountryChina
- Language:Chinese
-
Abstract:
Dexmedetomidine is an α2 adrenoceptor agonist and has cardioprotective effect,the mechanism of which is being studied.Increasing studies have proved the clinical value of dexmedetomidine in reducing postoperative complications and improving the prognosis of patients.Therefore,this review summarizes the cardiac protection mechanism of dexmedetomidine based on the existing studies and expounds the application of dexmedetomidine in the perioperative period of cardiovascular surgery.
