Comparison between Ultrasonography and CT in Diagnosis of Cervical Lymph Node Metastasis of Papillary Thyroid Carcinoma.
10.3881/j.issn.1000-503X.14135
- Author:
Jia-Hang ZHAO
1
;
Yan ZHANG
2
;
Yu-Kun LUO
1
;
Jie TANG
1
;
Yu LAN
2
;
Hong-Ying HE
2
;
Jing XIAO
2
;
Wen LI
1
;
Long-Xia WANG
1
Author Information
1. Medical School of Chinese PLA,Beijing 100853,China.
2. Department of Ultrasound,the First Medical Center of Chinese PLA General Hospital,Beijing 100853,China.
- Publication Type:Journal Article
- Keywords:
computed tomography;
diagnosis;
lymph node metastasis;
papillary thyroid carcinoma;
ultrasound
- MeSH:
Humans;
Lymphatic Metastasis/diagnostic imaging*;
Retrospective Studies;
Thyroid Cancer, Papillary/pathology*;
Thyroid Neoplasms/surgery*;
Tomography, X-Ray Computed;
Ultrasonography/methods*
- From:
Acta Academiae Medicinae Sinicae
2022;44(1):65-71
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of ultrasound and computed tomography (CT) in diagnosing cervical lymph node metastasis (CLNM) of papillary thyroid carcinoma (PTC). Methods The patients with PTC treated by surgery in the Chinese PLA General Hospital from January 2016 to January 2021 were selected for analysis.All the patients underwent preoperative ultrasound and CT examinations,the diagnostic values of which for CLNM were retrospectively analyzed. Results A total of 322 PTC patients were enrolled in this study,including 242 with CLNM and 80 with non-CLNM.The CLNM group and non-CLNM group had significant differences in age,tumor size,and maximum size of lateral CLNM (χ2=20.34,27.34,and 4.30,respectively,all P<0.001).For the central compartment,lateral compartment,and overall compartment,ultrasound diagnosis showed higher sensitivity (χ 2=82.26,P<0.001;χ2=114.01,P<0.001;χ2=82.26,P<0.001) and accuracy (χ2=20.27,P<0.001;χ2=15.56,P<0.001;χ2=44.00,P<0.001) than CT,and had no significant differences from ultrasound combined with CT (all P>0.05).However,ultrasound diagnosis had lower specificity than CT (χ2=17.01,P<0.001;χ2=21.29,P<0.001) in the central compartment and lateral compartment.Receiver operating characteristic curve analysis showed that in the central compartment,lateral compartment,and overall compartment,ultrasound diagnosis had larger AUC than CT (Z=2.99,P=0.003;Z=3.86,P<0.001;Z=4.47,P<0.001) and had no significant difference from ultrasound combined with CT (Z=1.87,P=0.062;Z=1.68,P=0.093;Z=1.61,P=0.107). Conclusions Ultrasound and CT have their own advantages in the diagnosis of central and lateral CLNM.In general,ultrasound has better performance than CT in the diagnosis of CLNM.
