Diffuse Ganglioneuromatosis of the Colon Presenting as a Large Subepithelial Tumor in Adults: Report of Two Cases.
10.4166/kjg.2015.66.2.111
- Author:
Tae Jun KIM
1
;
Hyun LIM
;
Ho Suk KANG
;
Sung Hoon MOON
;
Jong Hyeok KIM
;
Choong Kee PARK
;
Mi Jung KWON
;
Bong Hwa LEE
Author Information
1. Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea. hlim77@hallym.or.kr
- Publication Type:Case Reports
- Keywords:
Ganglioneuroma;
Subepithelial tumor;
Endoscopy;
Colon
- MeSH:
Adult;
Aged;
Colon/metabolism/*pathology;
Colonoscopy;
Ganglioneuroma/*diagnosis/metabolism/pathology;
Humans;
Immunohistochemistry;
Male;
S100 Proteins/metabolism;
Tomography, X-Ray Computed
- From:The Korean Journal of Gastroenterology
2015;66(2):111-115
- CountryRepublic of Korea
- Language:English
-
Abstract:
Colonic diffuse ganglioneuromatosis is a benign neoplastic condition characterized by disseminated, intramural, or transmural proliferation of neural elements involving the enteric plexuses, sometimes associated with von Recklinghausen's disease and other multiple tumor syndromes. Colonic diffuse ganglioneuromatosis is usually large, ranging from 1 to 17 cm, and thus can distort the surrounding tissue architecture as well as infiltrate the adjacent bowel wall. However, colonic diffuse ganglioneuromatosis is an exceptional finding in adults and only individual cases are reported in the literature. Herein, we report two unusual cases of adult patients with colonic diffuse transmural ganglioneuromatosis presenting as a large subepithelial tumor.
