A Case of Leukemoid Reaction in Pancreatic Ductal Adenocarcinoma.
10.4166/kjg.2015.66.2.116
- Author:
Kyong Hee HONG
1
;
Jun Kyu LEE
;
Seung Joo BYUN
;
Jae Woo JUNG
;
In Woong HAN
;
Jin Hee JUNG
;
Eo Jin KIM
Author Information
1. Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea. gerome@dumc.or.kr
- Publication Type:Case Reports
- Keywords:
Leukemoid reaction;
Paraneoplastic syndromes;
Pancreatic neoplasms
- MeSH:
Carcinoma, Pancreatic Ductal/complications/*diagnosis;
Female;
Humans;
Leukocytes/cytology;
Leukocytosis/*complications;
Magnetic Resonance Imaging;
Middle Aged;
Pancreatic Neoplasms/complications/*diagnosis;
Positron-Emission Tomography;
Tomography, X-Ray Computed
- From:The Korean Journal of Gastroenterology
2015;66(2):116-121
- CountryRepublic of Korea
- Language:English
-
Abstract:
Leukemoid reaction is defined as leukocytosis exceeding 50,000 cells/mm3. When it occurs in a patient with a malignancy, secondary causes such as infections, drugs, hematologic diseases and hemorrhage need to be ruled out. After excluding such causes, paraneoplastic leukemoid reaction can be considered as a diagnosis of exclusion. Paraneoplastic leukemoid reactions have been described in association with lung, gastrointestinal, genitourinary and head and neck cancers. However, pancreatic cancer with leukemoid reaction has been rarely reported. We diagnosed a case of a 55-year-old Korean woman with extreme leukocytosis associated with advanced pancreatic cancer.