Advances of enzymes related to microbial cement.

Lei Wang; Xuxia Wang; Fei LI; Mingjuan Cui; Xiaoxu Yang; Min Yang; Yunjun Yan

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Advances of enzymes related to microbial cement.

Author: Lei WANG ¹ ; Xuxia WANG ¹ ; Fei LI ¹ ; Mingjuan CUI ² ; Xiaoxu YANG ¹ ; Min YANG ¹ ; Yunjun YAN ¹
Author Information

1. School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China.
2. School of Civil Engineering and Mechanics, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China.
Publication Type:Review
Keywords: carbonic anhydrase; enzyme; microbial cement; microbial induced calcium carbonate precipitation (MICP); urease
MeSH: Calcium Carbonate/metabolism*; Chemical Precipitation; Urease/metabolism*
From: Chinese Journal of Biotechnology 2022;38(2):506-517
CountryChina
Language:Chinese
Abstract: Microbial induced calcium carbonate precipitation (MICP) refers to the natural biological process of calcium carbonate precipitation induced by microbial metabolism in its surrounding environment. Based on the principles of MICP, microbial cement has been developed and has received widespread attention in the field of biology, civil engineering, and environment owing to the merits of environmental friendliness and economic competence. Urease and carbonic anhydrase are the key enzymes closely related to microbial cement. This review summarizes the genes, protein structures, regulatory mechanisms, engineering strains and mutual synergistic relationship of these two enzymes. The application of bioinformatics and synthetic biology is expected to develop biocement with a wide range of environmental adaptability and high performance, and will bring the MICP research to a new height.