Squamous Cell Carcinoma Originating from Frostbite-induced Osteomyelitis.
- Author:
Hyun HWANGBO
1
;
Taek Geun LEE
;
Se Won JUNG
;
Hyun Ho SON
;
Sook Kyung LEE
Author Information
1. Department of Dermatology, Maryknoll Medical Center, Busan, Korea. wowhbh@hanmail.net
- Publication Type:Case Report
- Keywords:
Squamous cell carcinoma;
Osteomyelitis;
Frostbite
- MeSH:
Amputation;
Biopsy;
Burns;
Carcinoma, Squamous Cell*;
Cicatrix;
Dermatology;
Drinking;
Fluorodeoxyglucose F18;
Frostbite;
Humans;
Keratinocytes;
Male;
Middle Aged;
Necrosis;
Neoplasm Metastasis;
Osteolysis;
Osteomyelitis*;
Positron-Emission Tomography;
Pressure Ulcer;
Skin;
Smoke;
Smoking;
Toes;
Ultrasonography;
Varicose Ulcer;
Walking;
Wounds and Injuries
- From:Korean Journal of Dermatology
2015;53(7):556-559
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Squamous cell carcinoma commonly originates from recalcitrant wound sites, including burn scars, pressure sores, stasis ulcers, osteomyelitis, and sites of frostbite. A 62-year-old male was referred to the dermatology department for skin necrosis of his right great toe and walking difficulty. He had a history of smoking, drinking alcohol, and frostbite of his right great toe 9 years prior, which deteriorated into osteomyelitis due to poor care. Although a skin biopsy was recommended before amputation, the two procedures were performed simultaneously due to a lack of toe function due to severe osteolysis. Biopsy of the amputated toe tip showed many lobules consisting of atypical keratinocytes with hyperchromatic nuclei, and severe dermal pleomorphism. After evaluation for distant metastasis, including a (99m) Tc-MDP bone scan, 18F-FDG positron emission tomography scan, computed tomography, and ultrasound, no metastasis was detected.
