Research progress of extracellular vesicles in the treatment of renal disease.
- Author:
Tao-Tao TANG
1
;
Lin-Li LYU
1
;
Bi-Cheng LIU
2
Author Information
1. Institute of Nephrology, Zhongda Hospital, Southeast University, Nanjing 210009, China.
2. Institute of Nephrology, Zhongda Hospital, Southeast University, Nanjing 210009, China. liubc64@163.com.
- Publication Type:Review
- MeSH:
Cell Communication;
Drug Delivery Systems;
Extracellular Vesicles;
Humans;
Kidney Diseases/therapy*
- From:
Acta Physiologica Sinica
2022;74(1):67-72
- CountryChina
- Language:Chinese
-
Abstract:
Extracellular vesicles (EVs) are lipid bilayer-enclosed structures containing diverse bioactive cargoes that play a major role in intercellular communication in both physiological and pathological conditions. Currently, the field of EV-based therapy has been rapidly growing, and two main therapeutic uses of EVs can be surmised: (i) exploiting stem cell-derived EVs as therapeutic agents; and (ii) employing EVs as natural therapeutic vectors for drug delivery. This review will discuss the recent advances in EV-based therapy in the treatment of renal disease.
