Hepatitis D: advances and challenges.
10.1097/CM9.0000000000002011
- VernacularTitle:Hepatitis D: advances and challenges
- Author:
Zhijiang MIAO
1
;
Zhenrong XIE
2
;
Li REN
3
;
Qiuwei PAN
1
Author Information
1. Postgraduate School Molecular Medicine, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.
2. Biobank, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, China.
3. Department of Obstetrics and Gynecology, The First People's Hospital of Yunnan Province, Kunming, Yunnan 650031, China.
- Publication Type:Review
- MeSH:
Carcinoma, Hepatocellular/complications*;
Hepatitis B virus;
Hepatitis D/epidemiology*;
Hepatitis Delta Virus/genetics*;
Humans;
Liver Cirrhosis/etiology*;
Liver Neoplasms/complications*
- From:
Chinese Medical Journal
2022;135(7):767-773
- CountryChina
- Language:English
-
Abstract:
Hepatitis D virus (HDV) infection causes the most severe form of viral hepatitis with rapid progression to cirrhosis, hepatic decompensation, and hepatocellular carcinoma. Although discovered > 40 years ago, little attention has been paid to this pathogen from both scientific and public communities. However, effectively combating hepatitis D requires advanced scientific knowledge and joint efforts from multi-stakeholders. In this review, we emphasized the recent advances in HDV virology, epidemiology, clinical feature, treatment, and prevention. We not only highlighted the remaining challenges but also the opportunities that can move the field forward.
