Outcomes in randomized controlled trials of acupuncture for vascular cognitive impairment during recent five years.
10.13703/j.0255-2930.20210326-0002
- Author:
Xin-Yun ZENG
1
,
2
;
Xing LIAO
3
;
Yun-Ling ZHANG
4
;
Zi-Xiu ZENG
5
;
Wei SHEN
4
;
Min ZHAN
6
;
Ying WANG
5
;
Fu-Hua HAN
5
;
Jing-Zi SHI
5
;
Xi-Yue LU
5
Author Information
1. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China
2. Graduate School, Beijing University of CM, Beijing 100029.
3. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
4. Xiyuan Hospital of China Academy of Chinese Medical Sciences.
5. Graduate School, Beijing University of CM, Beijing 100029.
6. Graduate School, China Academy of Chinese Medical Sciences.
- Publication Type:Journal Article
- Keywords:
acupuncture;
outcome;
randomized controlled trial (RCT);
vascular cognitive impairment (VCI)
- MeSH:
Acupuncture Therapy;
Cognitive Dysfunction/therapy*;
Humans;
Randomized Controlled Trials as Topic;
Treatment Outcome
- From:
Chinese Acupuncture & Moxibustion
2022;42(5):590-594
- CountryChina
- Language:Chinese
-
Abstract:
The existing problems in the outcomes of randomized controlled trials (RCTs) of acupuncture for vascular cognitive impairment (VCI) during recent five years are analyzed and suggestions are proposed. The RCTs of acupuncture for VCI were selected in PubMed, EMbase, Cochrane Library, Clinical Trials, CNKI database, Wanfang database, VIP database, SinoMed database and Chinese Clinical Trial Registry (ChiCTR) from January 1, 2015 to September 14, 2020. The outcomes were extracted and analyzed. As a result, 21 RCTs were included and the outcomes used were divided into 9 categories: clinical symptom/sign indexes, quality of life indexes, neuroimaging indexes, neuroelectrophysiology indexes, blood biochemical indexes, hemorheology indexes, TCM syndrome score indexes, clinical efficacy indexes, and safety indexes. Among them, the top three of the most used outcomes were clinical symptoms/signs indexes (21, 100.0%), clinical efficacy indexes (14, 66.7%) and quality of life indexes (12, 57.1%). In the RCTs of acupuncture for VCI, attention should be paid to distinguish the primary outcomes and secondary outcomes, adopt objective and standardized efficacy evaluation, and give consideration to report the outcomes of safety, health economic and TCM characteristic indexes.
