Investigation on the mechanism of acupuncture in treatment of diabetes mellitus type 2 based on the network of islet macrophages-pancreatic adipose cells-islet β cells.
10.13703/j.0255-2930.20210126-k0004
- Author:
Yun LIU
1
;
Tian-Cheng XU
1
;
Zhi YU
1
;
Bin XU
1
Author Information
1. Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, China.
- Publication Type:Journal Article
- Keywords:
acupuncture;
diabetes mellitus type 2;
islet β cell;
macrophage;
pancreatic adipose cell
- MeSH:
Acupuncture Therapy;
Diabetes Mellitus, Type 2/therapy*;
Humans;
Insulin-Secreting Cells/pathology*;
Islets of Langerhans/pathology*;
Macrophages
- From:
Chinese Acupuncture & Moxibustion
2022;42(4):433-436
- CountryChina
- Language:Chinese
-
Abstract:
To explore the possible new mechanism of acupuncture in the treatment of diabetes mellitus type 2 (T2DM) based on the islet inflammatory response. Islet macrophages, pancreatic adipose cells and islet β cells all participate in the pathogenesis of T2DM, and the three could form a network interaction. Acupuncture could regulate the functional phenotype of islet macrophages, improve the ectopic deposition of pancreatic adipose and repair the function of islet β cells, and play a unique advantage of overall regulation. It is suggested that acupuncture can be a potential treatment strategy for T2DM.
