Tongdu Tiaoshen acupuncture combined with carotid endarterectomy for carotid artery stenosis: a randomized controlled trial.
10.13703/j.0255-2930.20210202-k0007
- Author:
Li-da ZHANG
1
;
Wei HAN
1
;
Zhi-Bo GAO
2
;
Zhao-Hong ZHU
3
;
Ying WANG
4
;
Guo-Qing ZHANG
4
;
Ling ZHANG
4
;
Jun-Yu ZHANG
5
;
Fo-Ci LUO
6
;
Ting-Ting TONG
6
Author Information
1. Department of TCM, Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou 510370, Guangdong Province, China.
2. Department of Neurosurgery, Anhui Fuyang People's Hospital.
3. Department of Vascular Surgery, Anhui Huaibei People's Hospital.
4. Department of Encephalopathy, Second Affiliated Hospital of Anhui University of CM.
5. Department of Geriatrics, Second Affiliated Hospital of Anhui University of CM.
6. School of Graduate, Anhui University of CM.
- Publication Type:Randomized Controlled Trial
- Keywords:
Tongdu Tiaoshen;
acupuncture;
carotid artery stenosis;
carotid endarterectomy;
randomized controlled trial (RCT)
- MeSH:
Acupuncture Points;
Acupuncture Therapy;
Carotid Intima-Media Thickness;
Carotid Stenosis/therapy*;
Endarterectomy, Carotid;
Humans;
Treatment Outcome
- From:
Chinese Acupuncture & Moxibustion
2022;42(2):121-125
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical therapeutic effect of Tongdu Tiaoshen acupuncture combined with carotid endarterectomy (CEA) and simple CEA on carotid artery stenosis (CAS).
METHODS:A total of 60 patients with CAS were randomized into an observation group (30 cases, 2 cases dropped off) and a control group (30 cases, 3 cases dropped off). Both groups were treated with eversion CEA (eCEA). The conventional treatment of internal medicine and antiplatelet drugs i.e. aspirin enteric-coated tablet and clopidogrel hydrogen sulfate tablet were given in the control group for 4 weeks. On the basis of the treatment in the control group, Tongdu Tiaoshen acupuncture was applied at Baihui (GV 20), Fengfu (GV 16), Yamen (GV 15), cervical Jiaji (EX-B 2), Dazhui (GV 14), etc. in the observation group, once a day, 1-day rest was taken after 6-day treatment, 2 weeks were as one course and totally 2 courses were required. The carotid intima-media thickness (IMT) before and after treatment was detected by ultrasonic diagnostic apparatus, the TCM symptom score was compared before and after treatment and in the follow-up of 6 months after treatment, the clinical efficacy was evaluated in the two groups. The occurrence of endpoints within 1 year was recorded.
RESULTS:After treatment, the carotid IMT and TCM symptom scores were decreased compared before treatment in the both groups (P<0.05), and the changes in the observation group were greater than the control group (P<0.05). In the follow-up, the TCM symptom scores were decreased compared before treatment in the both groups (P<0.05). The total effective rate was 96.4% (27/28) in the observation group, which was superior to 88.9% (24/27) in the control group (P<0.05). There were 1 case of stoke in the observation group and 2 cases of stroke in the control group within 1-year follow-up, and there was no significant difference in the number of endpoints between the two groups within 1 year (P>0.05).
CONCLUSION:Tongdu Tiaoshen acupuncture combined with CEA can effectively reduce the IMT in patients with CAS, improve the TCM symptom score, the efficacy is superior to simple CEA treatment.
