Effect of Botulinum Toxin Type A on Spastic Hamstring in Children with Cerebral Palsy
10.3969/j.issn.1006-9771.2014.05.006
- VernacularTitle:A型肉毒毒素对脑性瘫痪患儿腘绳肌痉挛的疗效
- Author:
Jianjun LIU
1
,
2
;
Bingyu XI
1
,
2
;
Shurong JI
1
,
2
;
Weihong WU
1
,
2
;
Yan ZHANG
1
,
2
;
Fanyong ZENG
1
,
2
;
Nanling LI
1
,
2
Author Information
1. Capital Medical University School of Rehabilitation Medicine, Beijing Bo'
2. ai Hospital, China Rehabilitation Research Centre, Beijing 100068, China
- Publication Type:Journal Article
- Keywords:
cerebral palsy, spasticity, hamstring, Botulinum toxin type A, gait analysis, gross motor fucntion
- From:
Chinese Journal of Rehabilitation Theory and Practice
2014;(5):417-419
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Botulinum toxin type A (BTX-A) injection on spastic hamstring in the children with cerebral palsy. Methods 39 cerebral palsy children with spastic hamstring were divided into control group (n=20) and experimental group (n=
19). The control group accepted physical therapy, while the experimental group accepted BTX-A injection in affected hamstring in addition.They were assessed with modified Ashworth Scale (MAS), Gross Motor Fucntion Measure (GMFM-88) and flexion angle of knee joints before and after treatment. Results The scores of MAS and GMFM-88, and flexion angle of knee joints improved significantly 6 weeks after treatment in the experimental group (P<0.05), and improved more than that in the control group (P<0.05). Only the score of GMFM-88 improved significantly in the control group (P<0.05). Conclusion BTX-A injection can relieve hamstring spasticity in children with cerebral palsy, which may be helpful to correct abnormal gait and improve the motor function.
