Research progress on the biotransformation of flavonoid glycosides in Epimedii Folium
- VernacularTitle:淫羊藿黄酮苷类化合物生物转化的研究进展
- Author:
Yuhang ZHANG
1
;
Wang CHEN
1
,
2
;
Zili FENG
1
,
2
;
Hongchao YUAN
3
;
Xiaolin GAO
4
;
Cuiping WANG
5
Author Information
1. School of Bioscience and Engineering，Shaanxi University of Technology，Shaanxi Hanzhong 723000，China
2. Shaanxi Provincial Key Lab of Bio-resource，Shaanxi University of Technology，Shaanxi Hanzhong 723000，China
3. Shaanxi Jinhuifang Traditional Chinese Medicine Technology Company，Shaanxi Hanzhong 723000，China
4. Shaanxi Tianrangu Biotechnology Co.，Ltd.，Shaanxi Hanzhong 723000，China
5. Shaanxi Tiangu Pharmaceutical Co.，Ltd.，Shaanxi Hanzhon g 723000，China
- Publication Type:Journal Article
- Keywords:
Epimedii Folium;
flavonoid glycosides;
low glycoside;
biotransformation
- From:
China Pharmacy
2022;33(12):1525-1529
- CountryChina
- Language:Chinese
-
Abstract:
Flavonoid glycosides are the main active constituents of Epimedii Folium and its related plants. They can be divided into polyglycosides and low glycosides according to the number of glycosyl group. The polyglycosides of Epimedii Folium can be transformed into low glycosides after biotransformation ；pharmacological activities of low glycosides in anti-tumor ，tonifying kidney yang and anti-osteoporosis are stronger than those of polyglycosides. In this paper ， the research progress about biotransformation technology of flavonoid glycosides of Epimedii Folium was reviewed. It was found that the main biotransformation pathway of flavonoid glycosides of Epimedii Folium was to obtain low glycosides by removing glycosyl group ； related methods were mainly enzymatic hydrolysis and microbial transformation ，and also included plant cell transformation ，acid hydrolysis method and synthesis method.
