Stress Sensitive Signal Pathway Osteoprotegerin/Receptor Activator of Nuclear Factor-κB ligand/Receptor Activator of Nuclear Factor-κB and Osteoporosis (review)
10.3969/j.issn.1006-9771.2014.03.013
- VernacularTitle:骨保护素/核因子-κB受体活化因子配体/核因子-κB受体活化因子信号通路与骨质疏松的研究进展
- Author:
Shengcun LI
1
;
Jie BAO
1
;
Jing WANG
1
;
Guoxiang WANG
1
Author Information
1. School of Physical Education of Soochow University, Suzhou 215021, Jiangsu, China
- Publication Type:Journal Article
- Keywords:
osteoporosis, stress, osteoprotegerin, receptor activator of nuclear factor-κB ligand, receptor activator of nuclear factor-κB, signal pathway, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2014;(3):250-252
- CountryChina
- Language:Chinese
-
Abstract:
Exercise is benefic for osteoporosis, without clear molecular biology mechanism. The osteoprotegerin/receptor activator of nuclear factor-κB ligand/receptor activator of nuclear factor-κB (OPG/RANKL/RANK) signal pathway contributes to osteoporosis, which can be mediated by mechanical force. Research progress on osteoporosis and the stress sensitive signal pathway OPG/RANKL/RANK were reviewed in this paper.