Approach to Hospitalized Patients with Fever and Skin Eruption: A Retrospective Analysis of Clinical Features
- Author:
Soo-Kyung LEE
1
;
Ho-Young KIM
;
Jae-Ho LEE
;
Myoung-Shin KIM
;
Un-Ha LEE
Author Information
1. Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea
- Publication Type:Original Article
- From:Korean Journal of Dermatology
2022;60(2):99-105
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:Fever and skin eruption are common manifestations in patients; however, assessing them can be challenging because of the wide range of differential diagnosis.
Objective:We aimed to obtain tips that could assist in differential diagnoses in patients with fever and skin eruption through the analysis of clinical features.
Methods:Medical records of hospitalized patients who had fever and skin eruption were examined from January 2010 to December 2019.
Results:The patients of the adverse drug reaction group were older (p=0.024), and they had underlying diseases (p<0.001), whole body skin eruption (p=0.018), elevated alanine aminotransferase (p=0.027). The autoimmune disease group was associated with longer total fever and skin eruption duration (p=0.049, 0.037), leukocytosis (p=0.015), and neutrophilia (p=0.006). Infectious erythema group was associated with targetoid lesions (p=0.003).
Conclusion:Clinicians should examine patients with fever and skin eruption, considering that there may be various causes. This can be assisted by delicate skin exam and laboratory tests.