Comparison between Screening Cells Including Dia and Mia Antigen for Unexpected Antibody Screening
10.17945/kjbt.2022.33.1.4 6
- Author:
Kyung-Hwa SHIN
1
;
Hyung Hoi KIM
;
Hyun-Ji LEE
;
Hyerim KIM
Author Information
1. Department of Laboratory Medicine, Pusan National Univiesity Hospital, Busan, Korea
- Publication Type:Letters to the Editor
- From:Korean Journal of Blood Transfusion
2022;33(1):46-49
- CountryRepublic of Korea
- Language:English
-
Abstract:
The Dia and Mia antigens have been detected in Koreans with a frequency of 6.4∼14.5% and 0.9%, respectively. This study evaluated the effectiveness of different screening cells using the cells with Diaand Mia antigens for unexpected antibody screening. An unexpected antibody-screening test was performed separately using different screening cells, including the Dia antigen (Panel D) and Mia antigen (Panel M). A total of 2,077 specimens from 1,847 patients were collected, among which 49 (2.32%) and 43 (2.08%) were positive using Panel D and Panel M, respectively. Twenty-seven patients were positive with both panels, 2012 were negative with both panels, and thirty-eight patients showed a discordant result. The suspected anti-Diaand anti-Mia were detected in 4 (0.19%) and 5 (0.24%) patients, respectively. Therefore, the frequency of anti-Dia and anti-Mia antibodies in this study may be helpful for selecting unexpected antibody screening reagents.
