The Effects of Bronchiectasis on Asthma Exacerbation.
10.4046/trd.2014.77.5.209
- Author:
Hye Ran KANG
1
;
Gyu Sik CHOI
;
Sun Jin PARK
;
Yoon Kyung SONG
;
Jeong Min KIM
;
Junghoon HA
;
Yung Hee LEE
;
Byoung Hoon LEE
;
Sang Hoon KIM
;
Jae Hyung LEE
Author Information
1. Division of Pulmonology and Allergy, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine, Seoul, Korea. medijae@eulji.ac.kr
- Publication Type:Original Article
- Keywords:
Bronchiectasis;
Asthma;
Disease Exacerbation
- MeSH:
Asthma*;
Bronchiectasis*;
Disease Progression;
Emergency Service, Hospital;
Hospitalization;
Humans;
Incidence;
Prevalence
- From:Tuberculosis and Respiratory Diseases
2014;77(5):209-214
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Bronchiectasis and asthma are different in many respects, but some patients have both conditions. Studies assessing the effect of bronchiectasis on asthma exacerbation are rare. The aim of this study is to investigate the effect of bronchiectasis on asthma exacerbation. METHODS: We enrolled 2,270 asthma patients who were followed up in our hospital. Fifty patients had bronchiectasis and asthma. We selected fifty age- and sex-matched controls from the 2,220 asthma patients without bronchiectasis, and assessed asthma exacerbation and its severity based on the annual incidence of total asthma exacerbation, annual prevalence of steroid use, and frequency of emergency room visits and hospitalizations due to asthma exacerbation in each group. RESULTS: Fifty patients (2.2%) had bronchiectasis and asthma. The annual incidence of asthma exacerbation was higher in patients with asthma and bronchiectasis than in patients with asthma alone (1.08+/-1.68 vs. 0.35+/-0.42, p=0.004). The annual prevalence of steroid use (0.9+/-1.54 vs. 0.26+/-0.36, p=0.006) and the frequency of emergency room visits (0.46+/-0.84 vs. 0.02+/-0.13, p=0.001) due to asthma exacerbation were also higher in patients with asthma and bronchiectasis than in patients with asthma alone. CONCLUSION: Bronchiectasis is associated with difficult asthma control.
