A sinonasal yolk sac tumor in an adult
- Author:
Jaehoon SHIN
1
;
Ji Heui KIM
;
Kyeong Cheon JUNG
;
Kyung-Ja CHO
Author Information
- Publication Type:Case Study
- From:Journal of Pathology and Translational Medicine 2022;56(3):152-156
- CountryRepublic of Korea
- Language:English
- Abstract: Yolk sac tumors (YSTs), which are also called endodermal sinus tumors, are malignant tumors of germ cell origin. These tumors usually occur in the gonads, but 20% of cases have been reported at extragonadal sites. The head and neck is a rarely affected region that accounts for just 1% of all malignant tumors of germ cell origin. In addition, YSTs arise mostly in childhood. We present a rare pathologically pure case of primary adult YST in the sinonasal area. A 45-year-old male patient presented with a rapidly growing mass in the nasal cavity, which caused nasal obstruction and bloody post-nasal drip. The histopathologic features indicated pure YST, and immunohistochemical analysis revealed positive reactivity for Sal-like protein 4 and alpha-fetoprotein. Herein, we discuss the clinical, radiologic, and histologic features of this YST and review other cases of sinonasal YST in adults.
