Quantifying Bone Marrow Edema Adjacent to the Lumbar Vertebral Endplate on Magnetic Resonance Imaging: A Cross-Sectional Study of Patients with Degenerative Lumbar Disease
- Author:
Toshio NAKAMAE
1
;
Naosuke KAMEI
;
Yoshinori FUJIMOTO
;
Kiyotaka YAMADA
;
Takayuki TAMURA
;
Yuji TSUCHIKAWA
;
Taiki MORISAKO
;
Takahiro HARADA
;
Toshiaki MARUYAMA
;
Nobuo ADACHI
Author Information
- Publication Type:Clinical Study
- From:Asian Spine Journal 2022;16(2):254-260
- CountryRepublic of Korea
- Language:English
-
Abstract:
Methods:Patients with degenerative lumbar diseases, whose MRIs detected BME, were enrolled. On a T2-weighted fat-saturated MRI, BME appeared as a high-intensity region adjacent to the vertebral endplate. We calculated the contrast ratios (CRs) of BME and normal bone marrow using the signal intensities of BME, normal bone marrow, and the spinal cord. On computed tomography, we calculated Hounsfield unit (HU) values in the same area as BME, the sclerotic endplate, and normal bone marrow to assess bone density.
Results:There were 16 men and 14 women, with an average age of 73.5 years. The mean CRs of BME and normal bone marrow were −0.015±0.056 and −0.407±0.023, respectively. BME’s CR was significantly higher than that of normal bone marrow (p<0.01). The HU values in the same area as BME, the sclerotic endplate, and normal bone marrow were 251.9±24.6, 828.3±35.6, and 98.1±9.3, respectively; these values were significantly different from each other (p<0.01).
Conclusions:The CR on MRI is a useful quantitative assessment tool for BME in patients with degenerative lumbar diseases.
