Risk factors and protective factors in pediatric patients with allergic rhinitis
10.4168/aard.2022.10.2.73
- Author:
Yoon Hong CHUN
1
;
Minji KIM
;
Hyo-Bin KIM
;
Yeong-Ho RHA
;
Yang PARK
;
Yong Mean PARK
;
Myongsoon SUNG
;
Youn Ho SHIN
;
Hye Yung YUM
;
Kyung Suk LEE
;
Yong Ju LEE
;
Hye Mi JEE
;
Bong Seok CHOI
;
Sun Hee CHOI
;
Hyun Hee KIM
;
Author Information
1. Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea
- Publication Type:REVIEW
- From:Allergy, Asthma & Respiratory Disease
2022;10(2):73-79
- CountryRepublic of Korea
- Language:English
-
Abstract:
Among allergic diseases of the Korean pediatric population, allergic rhinitis shows the most rapidly increasing prevalence. Its economic burden is substantial in many Asian countries including South Korea. This investigation of its risk factors aims to reduce the socioeconomic burden by blocking exposure of susceptible individuals to identified causes. However, the risk factors of allergic rhinitis varied considerably depending on the seasons, geographical locations, and populations involved. This review article primarily deals with studies on the risk factors for allergic rhinitis in Korean children that were published during the last 10 years and additionally investigates associated large scale international studies. Our investigation identified several single-nucleotide polymorphisms, inhalant allergens, pollution, tobacco smoke, chemicals, and family affluence as risk factors for allergic rhinitis. In contrast, breastfeeding, older sibling, and microbial diversity were protective factors against allergic rhinitis. This suggests that various genetic and environmental factors might affect the manifestation and presentation of allergic rhinitis complexly. These findings are beneficial as they can provide insights into modifiable risk factors that may hinder the development of allergic rhinitis.
