Risk factors for herb-induced liver injury
10.3969/j.issn.1001-5256.2022.05.044
- VernacularTitle:中药相关肝损伤的风险因素
- Author:
Yan YANG
1
;
Feilin GE
2
;
Qian HUANG
3
;
Rui ZENG
1
;
Xinyue ZHANG
1
;
Qin SUN
1
,
4
Author Information
1. School of Integrated Traditional Chinese and Western Medicine, Southwest Medical University, Luzhou, Sichuan 646000, China
2. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China
3. School of Pharmacy, Southwest Medical University, Luzhou, Sichuan 646000, China
4. Drug Research Center of Integrated Traditional Chinese and Western Medicine, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China
- Publication Type:Reviews
- Keywords:
Drugs, Chinese Herbal;
Liver Injury;
Risk Factors;
Drug Safety
- From:
Journal of Clinical Hepatology
2022;38(5):1183-1187
- CountryChina
- Language:Chinese
-
Abstract:
Drug-induced liver injury (DILI) is one of the common adverse drug reactions and is the main cause of withdrawal of drugs after marketing, which has attracted more and more attention of the public, and herb-induced liver injury (HILI) is a special type of DILI. In recent years, the frequent occurrence of HILI not only seriously endangers the health of patients, but also causes the controversy over the safety of traditional Chinese medicine. Therefore, this article reviews the potential risk factors for HILI from the three aspects of "patient", "drug", and "use", so as to provide a basis for the objective identification, prevention, and control of HILI and a reference for the construction of traditional Chinese medicine pharmacovigilance system represented by liver injury.
