Role of exercise-induced autophagy in prevention and treatment of nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2022.05.038
- VernacularTitle:运动诱导细胞自噬在非酒精性脂肪性肝病防治中的作用
- Author:
Yuesheng LIAO
1
;
Lili BAI
1
Author Information
1. School of Physical Sciences, Tianjin Normal University, Tianjin 300387, China
- Publication Type:Reviews
- Keywords:
Non-alcoholic Fatty Liver Disease;
Autophagy;
Exercise
- From:
Journal of Clinical Hepatology
2022;38(5):1156-1160
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic fatty liver disease (NAFLD) is a metabolic disease characterized by chronic liver damage. Epidemiological surveys have shown that the incidence rate of NAFLD is increasing constantly and NAFLD has become a serious threat to human life and health. Studies have shown that autophagy dysregulation is an important pathophysiological mechanism of NAFLD, and exercise, as an important non-pharmacological treatment, can prevent and treat NAFLD by inducing autophagy, but its exact mechanism is still unclear. This article summarizes the theoretical studies and application results related to the association between autophagy and NAFLD, the effect of exercise-induced autophagy on NAFLD, and its potential molecular mechanism, in order to provide a theoretical reference for the prevention and treatment of NAFLD.
