The Effect of Mokuboito in the Puerperium Lung Edema
- VernacularTitle:産褥期肺水腫における木防已湯の効果
- Author:
Isao FUKUDA
1
;
Hideyuki NAKATA
2
;
Munetaka KUSAKADO
3
;
Takaaki KOSUGE
4
Author Information
- Keywords: mokuboito; pulmonary edema during puerperium
- From:Kampo Medicine 2020;71(4):352-361
- CountryJapan
- Language:Japanese
- Abstract: Mokuboito is a Kampo formulation consisting of four flavors of Sinomeni Caulis Radix (防已), Gypsum Fibrosum (石膏), Cinnamomi Cortex (桂皮) and Ginseng Radix (人参). From a modern medical interpretation of the source “Kinkiyoryaku” it can be indicated for pulmonary edema, and if administered early in the onset, respiratory management by tracheal intubation can be avoided, which may contribute to improving the patient's QOL. We experienced 10 cases of pulmonary edema that occurred during the postpartum period and were able to avoid tracheal intubation with mokuboito already. All patients complained of dyspnea and moist rales were heard. Their chest X-rays showed decreased permeability of the lung field and increased pulmonary vascular shadow, increased cardiothoracic ratio (CTR), costophrenic angle (CP angle) blunting, therefore, they were diagnosed as pulmonary edema. After X-ray confirmation, mokuboito was administered, and in 6 cases,the subjective symptoms decreased from 7 to 4 in NRS (numerical rating scale), the CTR decreased from 60 to 40%, and CP angle, lung field findings, moist rales also improved. In 3 cases, mokuboito+choreito or mokuboito+choreito+choijokito were administered, and the X-ray findings were similarly improved. Mokuboito was useful for respiratory management of pulmonary edema during puerperium.
