The Effect of Equine Placental Extract on Anti-skin Aging Activity
- VernacularTitle:ウマ胎盤抽出物の皮膚における抗老化活性
- Author:
Yoshinobu TSURUTA
1
;
Eiichi HIRANO
2
;
Hideya ANDO
1
Author Information
- Keywords: Placental extract; Photo-aging; Reactive oxygen species; Skin fibroblast cell; Antioxidant
- From:Japanese Journal of Complementary and Alternative Medicine 2022;19(1):41-45
- CountryJapan
- Language:Japanese
- Abstract: In the present study, we assessed the antiaging effect of equine placental extract (ePE) on dermal fibroblasts and found that it markedly suppressed the appearance of β-galactosidase-positive cells among the senescent cells induced by repeated hydrogen peroxide exposure or ultraviolet A irradiation. Moreover, the efficacy of ePE treatment was similar to that of an antioxidant, N-acetylcysteine. Thus, owing to its antioxidant effect, ePE can be used as an antiaging agent, particularly for the dermis.
