Methodological study of rapid health technology assessment of drugs ：taking antitumor drugs as an example
- VernacularTitle:药物快速卫生技术评估方法学研究——以抗肿瘤用药为例
- Author:
Mengna LIU
1
;
Bin WU
2
;
Dandan AI
3
;
Qian XU
3
;
Xue LI
3
;
Jinyu CHEN
3
;
Wudong GUO
1
Author Information
1. National Institute of Healthcare Security，Capital Medical University，Beijing 100037，China
2. Clinical Research Center，Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine，Shanghai 200127，China
3. China Health Development Research Center，National Health Commission of People’s Republic of China，Beijing 100044，China
- Publication Type:Journal Article
- Keywords:
anti-tumor drug use;
rapid health technology assessment;
health technology assessment;
multi-criteria decision
- From:
China Pharmacy
2022;33(11):1386-1391
- CountryChina
- Language:Chinese
-
Abstract:
OBJECT IVE To develop a rapid health technology assessment （rHTA）methodology of drugs based on evidence integration and value judgment ，which is suitable for China ’s national conditions. METHODS The literature review was adopted to study health technology assessment （HTA）and multi-criteria decision analysis （MCDA），and then rHTA method based on China ’s condition was formulated preliminarily with anti-tumor drugs ；the method of rHTA was demonstrated by expert consultation ； finally，the feasibility of rHTA was preliminarily verified taking the drugs for the treatment of non-small cell lung cancer as an example. RESULTS Established rHTA method combined the theory and principles of HTA and MCDA ：HTA method was used to guide the collection and synthesis of literature and real-world evidence ，while MCDA made the value measurements of achievable evidences by various stakeholders from different views ；it established the working process ，evaluation dimensions ，evaluation indicators and scoring system of rHTA. The feasibility of this method was verified by the drug example of treating non-small cell lung cancer. CONCLUSIONS A set of drug-driven rHTA methodology guidance based on HTA and MCDA is established. It can quickly collect and integrate evidence ，and provide evidence support for decision makers in a short time.
