Ocular images for neurodegenerative disease analysis
10.3980/j.issn.1672-5123.2022.6.11
- VernacularTitle:基于眼部影像的神经退行性疾病分析研究进展
- Author:
Ao-Wang Qiu
1
,
2
,
3
Author Information
1. 1The First Affiliated Hospital of Nanjing Medical University
2. Jiangsu Province Hospital, Nanjing 210029, Jiangsu Province, China|2School of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094, Jiangsu Province, China|3Children'
3. s Mental Health Research Center, the Affiliated Brain Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
- Publication Type:Journal Article
- Keywords:
neurodegenerative diseases;
optical coherence tomography;
optical coherence tomography angiography;
neuro-ophthalmology;
biomarkers
- From:
International Eye Science
2022;22(6):941-945
- CountryChina
- Language:Chinese
-
Abstract:
Retina and optic nerve both originate in brain, therefore they have the similar structure and functional characteristics of the brain. Exploring the performance of the central optic nervous disorder on the retina will be beneficial to uncovering the interaction mechanism between brain and eye. As an extension of the central nervous system, the retina contains ganglion cell, a special neuron, whose axon form the optic nerve and has access into the central nervous system. Therefore, the retina can be used as a mirror reflecting neurodegenerative diseases structurally and functionally. With the development of imaging technology, optical coherence tomography(angiography)has become the mainstream tool for ophthalmological clinical diagnosis due to its easy operation and low cost. In recent years, discovering biomarkers of neurodegenerative diseases, especially Alzheimer's disease, Parkinson's disease, multiple sclerosis and so on, in the retinal optical coherence tomography images has gradually become an emerging research direction. In this review, we summarized the research progress of neurodegenerative diseases analysis based on the retinal images in the past decade, and provide a prospect to inspire further research as far as possible.
- Full text:202206011.pdf
