Role of Notch Signaling Pathway in Neurogenesis in Central Nervous System (review)
10.3969/j.issn.1006-9771.2016.11.008.
- VernacularTitle:Notch信号通路在中枢神经系统神经发生过程中作用的研究进展
- Author:
Liliang ZOU
1
;
Kui WANG
1
;
Xianan MAN
1
;
Jianer CHEN
1
Author Information
1. Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China
- Publication Type:Journal Article
- Keywords:
Notch, signaling pathway, central nervous system, neurogenesis, neural stem cell, neural progenitor cell, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2016;22(11):1281-1284
- CountryChina
- Language:Chinese
-
Abstract:
The Notch signaling pathway plays a pivotal role in the process of neurogenesis in central nervous system. It not only maintains the appropriate number and proportion of neurons and glial cells in the growth and development of embryo, but also regulates the injured neural stem/progenitor cells to differentiate into neurons/glial cells of the adult nervous system, promoting the repair of the nervous system.
