Effectiveness of antiretroviral therapy for the first time on HIV/AIDS patients in Jiangyin
- VernacularTitle:江阴市HIV/AIDS患者首次接受抗病毒治疗效果分析
- Author:
Jianmei TANG
1
;
Hongda LU
1
;
Yin XU
1
;
Liang ZOU
1
Author Information
- Publication Type:Journal Article
- Keywords: HIV/AIDS patients; Antiretroviral treatment; Viral load; CD4-positive-Tlymphocytes
- From: Journal of Public Health and Preventive Medicine 2022;33(3):109-112
- CountryChina
- Language:Chinese
- Abstract: Objective To analyze the effect of HIV/AIDS patients receiving antiretroviral therapy (ART) for the first time in Jiangyin, and to provide a reference for further improvement of Jiangyin's AIDS antiretroviral treatment. Methods The historical cards and related information in the treatment management database of Jiangyin City's cases who received ART for the first time from 2005 to 2019 were collected and statistically analyzed. The changes in viral load and CD4+ T lymphocytes (CD4 cells) before and after treatment were compared. Results Among 652 patients receiving ART, 507 cases (77.76%) were successful in virological treatment. The median natural change rate of annual average CD4 cell count was 90.8 cells/μL/year (χ2=37.915, P<0.05; H=9.781, P<0.05). There were statistically significant differences in virological treatment and immune recovery between different age groups (χ2=10.713, P<0.05; H =10.394, P<0.05) and different baseline CD4 count layers. The results showed that age and baseline CD4 value were the influencing factors of treatment effect. Conclusion Age and baseline CD4 value can affect the effect of ART treatment. The older the age and the lower the baseline CD4 value, the worse the virological efficacy and the recovery effect of CD4 cells. It is suggested that the infected patients should be involved in ART in time, which is conducive to shorten the time of initial treatment and further improve the effect of antiviral treatment.
