Research Progress of MicroRNA in Spinal Cord Injury (review)

Wenhao Zhang; Jianjun LI; Degang Yang; Pincao Gao; Mingliang Yang; Liangjie DU; Feng Gao; Fang Tang; Changbin Liu; Dapeng LI; Xin Zhang; Jie Zhang

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Research Progress of MicroRNA in Spinal Cord Injury (review)

VernacularTitle:MicroRNA在脊髓损伤中的研究进展
Author: Wenhao ZHANG ^{1
,

2
,

3
,

4
,

5} ; Jianjun LI ^{1
,

2
,

3
,

4
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5} ; Degang YANG ^{1
,

2
,

3
,

4
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5} ; Pincao GAO ⁶ ; Mingliang YANG ^{1
,

2
,

3
,

4
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5} ; Liangjie DU ^{1
,

2
,

3
,

4
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5} ; Feng GAO ^{1
,

2
,

3
,

4
,

5} ; Fang TANG ⁶ ; Changbin LIU ^{1
,

2
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3
,

4
,

5} ; Dapeng LI ^{1
,

2
,

3
,

4
,

5} ; Xin ZHANG ^{1
,

2
,

3
,

4
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5} ; Jie ZHANG ^{1
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2
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3
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4
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5}
Author Information

1. 1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
2. 2. Department of Spinal and Neural Function Reconstruction, Beijing Bo'
3. ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
4. 3. Center of Neural Injury and Repair, Beijing Institute for Brain Disorders, Beijing 100068, China
5. 4. Beijing Key Laboratory of Neural Injury and Rehabilitation, Beijing 100068, China
6. 5. Hunan Medical University, Huaihua, Hunan 418000, China
Publication Type:Journal Article
Keywords: spinal cord injury, microRNA, gene expression, transcriptional regulation, biological markers, novel targets, review
From: Chinese Journal of Rehabilitation Theory and Practice 2017;23(6):649-653
CountryChina
Language:Chinese
Abstract: MicroRNAs are short non-coding RNAs that regulate and control the translation of target genes, and play an important role in gene expression involved in the development of spinal cord and spinal cord injury, which constitute novel targets for therapeutic intervention to promote repair and regeneration of the spinal cord, also they are the potential biomarkers of spinal cord injury. This article reviewed the mechanism of microRNAs and listed several microRNAs in spinal cord injury area.