Glial Choristoma in the Middle Ear and Mastoid Bone: A Case Report.
10.3346/jkms.2004.19.1.155
- Author:
Jong Im LEE
1
;
Ki Kwon KIM
;
Yoon Keun PARK
;
Kyung Yoon EAH
;
Jung Ran KIM
Author Information
1. Department of Pathology, Otolaryngology, College of Medicine, Dongguk University, Gyeongju, Korea. leego@mail.dongguk.ac.kr
- Publication Type:Case Report
- Keywords:
Choristoma;
Encephalocele;
Brain;
Neuroglia;
Ear, Middle
- MeSH:
Audiometry;
Brain/pathology;
Brain Diseases/*pathology;
Choristoma/*diagnosis;
Ear, Middle/*pathology;
Human;
Immunohistochemistry;
Male;
Mastoid/*pathology/surgery;
Middle Aged;
Neuroglia/*pathology;
Tomography, X-Ray Computed
- From:Journal of Korean Medical Science
2004;19(1):155-158
- CountryRepublic of Korea
- Language:English
-
Abstract:
Heterotopic brain tissue usually involves extracranial midline structures of the head and neck such as nose, nasopharynx, and oral cavity. Its occurrence in the non-midline structures, including middle ear, is rare. We described a 50-yr-old-man with heterotopic glial tissue in the middle ear and mastoid bone. The patient presented with progressive hearing loss for 8 yr. There was no history of congenital anomalies, trauma, or ear surgery. Computed tomography revealed a mass-like lesion with soft tissue density occupying the middle ear cavity and mastoid antrum. At the operation, a graywhite fibrotic mass was detected in the epitympanic area. Mesotympanum and ossicles were intact. The patient underwent left simple mastoidectomy with type I tympanoplasty. During operation, definite cranial bone defect or cerebrospinal fluid leakage was not found. Histologically, the lesion was composed of exclusively mature, disorganized glial tissue with fibrovascular elements in a rather loose fibrillary background. Glial tissue showed diffuse positive reaction for glial fibrillar acidic protein and S100 protein on immunohistochemical study.
