Advance in Metabolomics of Spinal Cord Injury (review)

VernacularTitle:脊髓损伤的代谢组学研究进展
Author: Xinle YANG ¹ ; Ming WANG ¹ ; Chengwei YANG ² ; Yajie XU ³ ; Ping ZHEN ²
Author Information

1. The Second Hospital of Lanzhou University, Lanzhou, Gansu 730000, China
2. Department of Orthopaedic, the Lanzhou General Hospital of PLA, Lanzhou, Gansu 730050, China
3. Henan Rong Jun Hospital, Xinxiang, Henan 453000, China
Publication Type:Journal Article
Keywords: spinal cord injury, metabolomics, biomarkers, review
From: Chinese Journal of Rehabilitation Theory and Practice 2018;24(8):904-908
CountryChina
Language:Chinese
Abstract: Spinal cord injury (SCI) often causes different degrees of sensory and motor dysfunction, resulting in permanent disability, with many complications and difficult to cure. Metabolomics, as a new developing technique, identifies specific biomarkers for diagnosis, treatment or prognosis judgement by analyzing the changes in the metabolites after individual stress, and can make the best treatment and rehabilitation program for the patients in the early stage of the disease. At present, some achievements have been made in the diagnosis, treatment and prognosis monitoring of spinal cord injury, and some potential biomarkers have been identified. However, the pathophysiology of spinal cord injury is not fully understood, and relevant biomarkers are also lacking in clinical trials.